Welcome to the CMCB Technology Platform

Advanced and sophisticated technologies, together with state-of-the-art equipment and trained dedicated personnel, are prerequisites for first class research in the fields of biotechnology and biomedicine. The nine Core Facilities of the CMCB Technology Platform (jointly run by B CUBE, BIOTEC and CRTD) provide access to superior technical and personnel resources through innovative management concepts. For further information click here.

Advanced Imaging

Advanced Imaging

The Advanced Imaging Facilities of CMCB provide access to, and expert training on highly specialized devices within the light microscopy and electron microscopy facilities. Furthermore the molecular imaging and manipulation facility as well as the histology facility complement the offered services. [details]

Biomolecular Synthesis

Biomolecular Synthesis

The Biomolecular Synthesis Facility provides high quality peptides services ranging from biomolecular synthesis and modifications to high throughput peptide array synthesis (SPOT method) for libraries. The SPOT synthesis is a unique method to generate large numbers of different peptides on cellulose membranes for use in arrays or screening libraries. [details]

Deep Sequencing

Deep Sequencing

The Deep Sequencing Facility offers high quality services for a diversity of Next Generation Sequencing based applications. These include RNA sequencing, especially from ultra-low input down to single cell sequencing, genomic re-sequencing, ChIP sequencing and targeted re-sequencing. Workflows from native samples to final data sets are established both on short read Illumina- and long read PacBio sequencing systems. [details]

Flow Cytometry

Flow Cytometry

The Flow Cytometry Facility offers access to state-of-the-art devices as well as services such as multi-color analysis, cell sorting, flow cytometry training and support in designing and analysis of experiments. [details]

Microstructure

Microstructure

The Microstructure Facility provides cutting edge technologies for micro-structuring of organic/inorganic materials, offering full set of skills and capabilities within photolithography, soft lithography, polymer microstructuring, thin film deposition and microfluidics. It focuses on developing collaborations with researchers, supporting research projects for the optimization of specific microfabrication steps or complete processes and devices. [details]

Molecular Analysis/Mass Spectrometry

Molecular Analysis/Mass Spectrometry

The Molecular Analysis Facility provides services and equipment to analyze the formation rate and strength of biomolecular interactions as well as services for the identification and structural analysis of biomolecules by mass spectrometry, including sequence analysis of peptides. [details]

Stem Cell Engineering

Stem Cell Engineering

The Stem Cell Engineering Facility provides iPS cell and isogenic iPS/ES cell lines generation, pluripotency characterization, and engineering (gene correction, reporters, knock in/outs) services to the scientific community. [details]

CRTD Facilities

These Facilities are run by CRTD and support as well as represent the research activities of independent research groups in advanced technological fields, providing know-how to other users on a collaborative basis. The main aim here is to focus on further improving access to specific instrumentation and know-how - explicitly in regard to the CRTD strategy to support basic research and enhance clinical application.

Good Manufacturing Practice (GMP)

Good Manufacturing Practice (GMP)

GMP compiles guidelines required in order to ensure high standards and reproducibility for the production of drugs. These guidelines provide minimum requirements that a pharmaceutical manufacturer must meet to assure that the products are of high quality and do not pose any risk to the consumer or public. GMP is a substantial prerequisite for a successful translation of basic research into clinical applications, like cellular therapies [details]

In Vivo Testing

In Vivo Testing

The In Vivo Testing Facility (ITF) offers screening-based services to assist researchers in developing high-throughput screening assays, in particular using zebrafish embryos. The Vertebrate Automated Screening Technology (VAST) is installed, which handles zebrafish embryos (2-5dpf) automatically for high-throughput imaging. The VAST is combined with high-speed and super-resolution Zeiss Cell Observer Spinning Disk Confocal System. [details]

Mass cytometry (CyTOF)

Mass cytometry (CyTOF)

The mass cytometry facility provides customized solutions for complex single cell profiling using CyTOF-technology to detect up to 45 biomarkers simultaneously, making it an ideal discovery tool for protein expression. The Facility offers assistance or whole workflow– from experimental design, panel testing and sample processing to complex data analysis. [details]