Microstructure - Publications


3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK

A. V. Taubenberger, S. Girardo, N. Träber, E. Fischer-Friedrich, M. Kräter, P. Rosendahl, Katrin Wagner, Thomas K., I. Richter, B. Haller, M. Binner, U. Freudenberg, C. Werner and J. Guck

Advanced Biosystems

High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry

B. Fregin, F. Czerwinski, D. Biedenweg, S. Girardo, S. Gross, K. Aurich and O. Otto

Nature Communication


Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

N. Träber, K. Uhlmann, S. Girardo, G. Kesavan, K. Wagner, J. Friedrichs, R. Goswami, K. Bai, M. Brand, C. Werner, D. Balzani, and J. Guck


Standardized microgel beads as elastic cell mechanical probes

S. Girardo, N. Traeber, K. Wagner, G. Cojoc, C. Herold, R. Goswami, R. Schluessler, S. Abuhattum, A. Taubenberger, F. Reichel, D. Mokbel, M. Herbig, M. Schuermann, P. Mueller, T. Heida, A. Jacobi, J. Thiele, C. Werner and J. Guck

Journal of Materials Chemistry B

Directionally biased sidestepping of Kip3/kinesin-8 is regulated by ATP waiting time and motor–microtubule interaction strength

A. Mitra, F. Ruhnowa, S. Girardo, and S. Diez


Real-time fluorescence and deformability cytometry — flow cytometry goes mechanics

P. Rosendahl, K. Plak, A. Jacobi, M. Kräter, N. Toepfner, O. Otto, C. Herold, M. Winzi, M. Herbig, Y. Ge, S. Girardo, K. S. Wagner, B. Baum and J. Guck

Nature Methods

Accurate evaluation of size and refractive index for spherical objects in quantitative phase imaging

P. Müller, M. Schürmann, S. Girardo, G. Cojoc, and J. Guck

Optic Express

Measuring Microtubule Supertwist and Defects by Three-Dimensional-Force-Clamp Tracking of Single Kinesin-1 Motors

M. Bugiel, A. Mitra, S. Girardo, S. Diez, and E. Schäffer

Nano Letters


3D correlative single-cell imaging utilizing fluorescence and refractive index tomography

M. Schürmann, G. Cojoc, S. Girardo, E. Ulbricht, J. Guck, P. Müller

Journal of Biophotonics

Numerical Simulation of Real-Time Deformability Cytometry to Extract Cell Mechanical Properties

M. Mokbel, D. Mokbel, A. Mietke, N. Träber, S. Girardo, O. Otto,J. Guck, S. Alan

ACS Biomaterials Science & Engineering


Three-Dimensional Motility of the Highly Processive Kinesin-8 Along the Microtubule Lattice

A. Mitra, F. Ruhnow, S. Girardo, D. Stefan

Biophysical Journal


Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment

A. Mietke, O. Otto, S. Girardo, P. Rosendahl, A. Taubenberger, S. Golfier, E. Ulbricht, S. Aland, J. Guck, E. Fischer-Friedrich

Biophysical Journal

Real-time deformability cytometry: On-the-fly cell mechanical phenotyping

O. Otto, P. Rosendahl, A. Mietke, S. Golfier, C. Herold, D. Klaue, S. Girardo, S. Pagliara, A. Ekpenyong, A. Jacobi, M. Wobus, N. Töpfner, U. F Keyser, J. Mansfeld, E. Fischer-Friedric, J. Guck

Nature Methods